Frank M. Longo, M.D., Ph.D.

Dr. Longo is Chairman of the Board and Co-founder of PharmatrophiX. Dr. Longo received his MD in 1981 and PhD in Neurosciences in 1983 from UC San Diego. He completed his neurology training in the Department of Neurology at UC San Francisco where he was then recruited as an assistant professor and promoted to professor and vice chair. From 2001 to 2005 he was chair of the Department of Neurology at the University of North Carolina-Chapel Hill and served as chair of the Department of Neurology and Neurological Sciences at Stanford University from 2006-2023. With support from the Alzheimer’s Drug Discovery Foundation, Alzheimer’s Association, Eastern North Carolina Chapter of the Alzheimer’s Association, the NIH-National Institute on Aging and generous donations, he and his team, along with co-inventor Dr. Stephen Massa MD, PhD at UCSF, pioneered the development of small molecules targeting neurotrophin receptors for the treatment of Alzheimer’s, Huntington’s diseases and other disorders. In 2005, while at UNC, he co-founded PharmatrophiX for the focus on commercial development of such compounds. Dr. Longo is the inaugural recipient of the Melvin R. Goodes Prize for Excellence in Alzheimer’s Drug Discovery. Dr. Longo serves in many advisory capacities including the National Advisory Council on Aging, NIH study sections, editorial boards, foundations, grant review boards and therapy evaluations.