About PharmatrophiX

PharmatrophiX (PTX) is a privately held biopharmaceutical company focused on the
development of disease-modifying small molecule drugs targeting mechanisms underlying
neurodegenerative and other disorders.

PTX is operated as a virtual biotech company in Menlo Park, CA executing drug development
through contracted work. This virtual model is recognized as an effective way of minimizing
overhead costs while efficiently achieving drug development milestones. PTX was founded in
2005 by Frank M. Longo, MD, PhD during his tenure at UNC - Chapel Hill. He serves as
Chairman of the Board of PTX and as a consultant. Seed funding and additional corporate
funding has been provided by the peer-reviewed biotech support program of the Alzheimer's
Drug Development Foundation (ADDF).

Developing small molecule drugs for

neurodegenerative and other diseases